Alloimmunization to Kell blood group system antigen owing to unmatched blood transfusion in a resource-poor setting
نویسندگان
چکیده
منابع مشابه
Alloimmunization to red blood cell antigens by transfusion.
et al. Hereditary fibrinogen A alpha-chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation. treatment, and prognosis of hereditary fibrinogen Aalpha-chain amyloidosis. Mutant fibrinogen A-alpha-chain associated with hereditary renal amyloidosis and peripheral neuropathy. and serial monitoring of human visceral amyloid deposits provide evidenc...
متن کاملStudy of Kell blood group genotype in alloimmiunized thalassemia patients
Abstract Background and Objectives Alloimmunization is the most serious problem in thalassemia patients and Anti-K is the most prevalent antibody in these patients. So accurate identification of this antigen can significantly decrease the rate of alloimmunization. Serological phenotyping is usually not reliable in multi-transfused patients. Molecular genotyping can overcome limitations of hema...
متن کاملRed Blood Cell Alloimmunization in Patients with Thalassemia Major and Intermediate in Southwest Iran
Background: Transfusion is the mainstay treatment of patients with thalassemia major and occasionally in thalassemia intermediate. Alloimmunization is an unwanted side effect of blood transfusion. The present study intended to determine the frequency of alloimmunization in patients with β- thalassemia major and thalassemia intermediate in Southwest Iran. Patients and Methods: This was a cross-...
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The objective of this study is to establish the mapping of blood group and phenotype Rhesus and Kell and compare it to the population of blood donors. Methodology: It is a prospective study performed in transfusion therapy unit (UTT) of the national blood transfusion center (NBTC) of Abidjan on sickle cell desease patients multitransfused between February and October 2013. The blood group ABO a...
متن کاملCharacterization of the blood group Kell (K1) antigen with a human monoclonal antibody.
A human monoclonal anti-Kell (K1) antibody secreted by an Epstein-Barr virus (EBV)-transformed B-cell line was used for binding studies and immunopurification of the K1 blood group antigen. The 125I-labeled antibody bound to 4 to 5 x 10(3) and 2.5 to 3 x 10(3) antigenic sites on K1K1 and K1K2 erythrocytes, respectively, with an affinity constant of 5 x 10(8) mol/L-1. Immunoprecipitation analysi...
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ژورنال
عنوان ژورنال: Immunohematology
سال: 2019
ISSN: 0894-203X,1930-3955
DOI: 10.21307/immunohematology-2019-148